Prozac is an anti-depressant and alcohol is categorised as a depressant. Also, if you drink alcohol while taking a certain type of antidepressant called an MAOI, your blood pressure could rise dramatically and could even cause a stroke. There seems to be no logic in taking anti-depressants and depressants at the same time. I haven’t had any alcohol whatsoever in that time because you are advised not too. Depression can also raise your odds of alcohol abuse . Operating machinery, driving and taking important decisions are impossible when mixing Prozac and alcohol. I’m getting to the stage where I think I would like to have a beer or two, nothing too crazy just a couple one evening. There are many different types of antidepressants, and each one affects the body in its own way. The main thing to consider is the different effects of each antidepressant. Alcohol use is associated with negative coping skills: Reaching for alcohol as a way to cope with depression can lead to severe drinking problems, including alcohol addiction. Because alcohol can cause depression on its own and make some antidepressants not work well, this could lead you to think about suicide. Alcohol is one of the most-commonly abused substances in the world. The prescription drug fluoxetine, most commonly known under the brand name Prozac, is typically prescribed to treat depression, anxiety, and obsessive-compulsive disorder.There is some research evidence to suggest that it has a marked effect on decreasing alcohol intake and, additionally, may be moderately effective in treating alcohol withdrawal syndrome. Depression is a very serious illness, and the symptoms can be debilitating. First and foremost, before looking at the interaction between alcohol and SSRI, people who are taking antidepressants should be careful with their alcohol use in general. Serotonin Syndrome and the Dangers of Mixing Alcohol and Antidepressants. Specific Types of Antidepressants and Alcohol. Prozac® affects the serotonin neurotransmitters, while alcohol can affect neurological pathways; in extreme cases of alcohol use disorder, such as alcoholism, chronic consumption can … Alcohol Abuse and Alcoholism. The main side-effects of fluoxetine include tiredness, impaired coordination, and alertness. The side effects of fluoxetine are thus somewhat similar to alcohol’s side effects. While taking antidepressants, this may cause problems. Drinking alcohol causes a temporary boost in serotonin. The dangers of mixing fluoxetine and alcohol. Key Points: Prozac and Alcohol. Combining antidepressants like Prozac and alcohol have been known to cause people to become pathologically intoxicated, even though they may have had only one or two drinks. Combining alcohol and fluoxetine … This could lead to an increase in suicidal thoughts and actions. 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